Concept
P53 upregulated modulator of apoptosis
Related lectures (20)
DNA Damage Response and Tumor Suppressor Genes
Delves into DNA damage response, tumor suppressor genes, and mutant P53 in cancer.
Cancer Biology: Base Excision Repair
Covers cancer biology topics on base excision repair, cellular responses to DNA damage, p53 regulation, and apoptosis mechanisms.
Programmed Cell Death: Mechanisms and Implications
Explores programmed cell death mechanisms, including apoptosis and autophagy, with a focus on their implications in various organisms and regeneration processes.
Replicative Immortality
Explores replicative immortality in cancer cells, focusing on telomere erosion, telomerase activity, and the role of p53 in maintaining genomic stability.
DNA Damage and Repair
Covers DNA damage types, repair mechanisms, UV-induced damage, survival curves, NER deficiency consequences, tumor suppressor genes, and cancer prevention.
Activation and Differentiation of T Cells
Explores the activation and differentiation of T lymphocytes, focusing on naive T cells recognizing antigens and differentiating into effector and memory cells.
B Cell T-Dependent Response: DifferentiationMOOC: Introduction à l'immunologie (part 1)
Explores B cell differentiation pathways, affinity maturation, and germinal center reactions.
Immunological Tolerance
Explores immunological tolerance, mechanisms of self-tolerance, regulatory T cells, and factors leading to autoimmunity.
Tumor Suppressor p53
Explores the tumor suppressor gene p53, its functions, regulation, and implications for cancer.
Evading Growth Suppression: TGFB Signaling
Explores how cells evade growth suppression, focusing on TGFB signaling and the role of tumor suppressors like PTEN and p53.