Explores the evolution of DNA sequencing techniques, from shotgun sequencing to real-time PCR, emphasizing the importance of direct RNA sequencing and the challenges of repetitive DNA sequences.
Explores tools and models for Next-Generation Sequencing data analysis, covering DNA sequencing technologies, data analysis pipelines, and statistical models.
Introduces BioMEMS, covering applications like DNA separation, protein analysis, and neuroelectronic implants, along with key numbers in biology and challenges in system integration.
Explores single molecule sequencing strategies, including sequencing by synthesis and real-time sequencing based on zero mode waveguides, as well as DNA translocation through nanopores.