DNA Damage Response and Tumor Suppressor Genes

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Multi-step Tumor Progression: De Palma

Explores the multi-step progression of tumors, from cancer incidence rates to tumor initiators and promoters.

Metabolic Signaling: Challenges & Future Directions

Explores metabolic signaling, the Warburg effect, and pathway rewiring in proliferating cells.

DNA Repair Mechanisms

Covers mutations, classification, causes, and repair mechanisms of DNA, including spontaneous and induced mutations, replication errors, and DNA damage.

Replicative Immortality

Explores replicative immortality in cancer cells, focusing on telomere erosion, telomerase activity, and the role of p53 in maintaining genomic stability.

Cellular Senescence and Tumor Progression

Explores cellular senescence, oncogene activation, DNA damage response, and telomere dysfunction in cancer suppression pathways.

Genetic Instability: De Palma

Explores genetic instability in cancer, multi-step progression, repair mechanisms, and cancer stem cells.

Angelman Syndrome: Genetic Mechanisms

Explores DNA methylation analysis and gene mutations in Angelman Syndrome.

Neurogenetics: Building blocks of a gene

Explores 21st-century neurogenetics and the building blocks of genes, emphasizing the impact of environment and genetics on neurodevelopment.

Regulation of Metabolism: Molecular Mechanisms

Explores the molecular mechanisms regulating enzyme activity and gene expression in metabolism.

Prader-Villy Syndrome: Genetic Mechanisms and Clinical Implications

Explores the genetic basis of Prader-Villy syndrome and its comparison with Angelman syndrome, emphasizing DNA methylation patterns and chromosomal abnormalities.