DNA Repair Mechanisms

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Genetic Instability: De Palma

Explores genetic instability in cancer, multi-step progression, repair mechanisms, and cancer stem cells.

Mutations and Cancer: The Role of P53 and HPV

Covers mutations, the role of P53 in cancer, and HPV's impact on tumorigenesis.

Telomeres and Cancer

Explores telomeres' role in cancer biology, covering telomerase, replication problems, ALT pathway, and Nobel Prize-winning discoveries.

BRCA2 Mutations: Mechanisms and Implications

Explores BRCA2 mutations, DNA repair mechanisms, and therapeutic implications for BRCA mutant cancers.

RNA Polymerases and DNA Repair Mechanisms

Explores RNA polymerases, ATP production, DNA repair, and UV light effects on DNA.

Self-attraction of DNA: Mediated Interactions

Discusses the self-attraction of DNA and its mediated interactions.

DNA and RNA Structure

Explores the composition and structure of DNA and RNA, including DNA replication and the genetic code.

Alternative Strategies for SMA Gene Therapy

Explores alternative strategies for SMA gene therapy, including antisense oligonucleotides and genome editing.

DNA Mutations: Mechanisms and Consequences

Explores DNA mutation mechanisms, including replication errors and induced mutations by mutagens, emphasizing their role in genetic diversity.

Genome Editing: CRISPR-Cas Applications

Explores the applications of CRISPR-Cas in genome editing, focusing on engineering bacterial genomes, curing genetic diseases, guide RNA simplicity, Cas9 specificity, DNA damage mechanisms, and base editing.