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Explores liquid chromatography principles, various chromatographic techniques, HPLC components, and the comparison between off-gel IEF and SCX chromatography.
Covers the process of expressing and purifying proteins, including the importance of studying protein function, folding, interactions, sequence, and structure.
Explains chromatography principles for protein purification, covering peak broadening causes, band broadening components, and common stationary phases.
Analyzes a mutant DDX3 enzyme's ATPase activity and inhibitor development, covering RNA chaperones, crystal structures, and mass spectrometry-based protein profiling.
Explores proteinopathy mapping, connecting proteotoxicity to intrinsic functions of aggregation-prone proteins, with a focus on alpha-synuclein and Parkinson's Disease.