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Explores the applications of CRISPR-Cas in genome editing, focusing on engineering bacterial genomes, curing genetic diseases, guide RNA simplicity, Cas9 specificity, DNA damage mechanisms, and base editing.
Explores the definition, frequency, classification, and types of cancer, including carcinomas, sarcomas, hematopoietic malignancies, and neuroectodermal tumors.
Explores DNA repair mechanisms, highlighting the excision repair pathway and the correction of DNA lesions induced by UV radiation and ionizing radiation.
Explores the genetic basis of Prader-Villy syndrome and its comparison with Angelman syndrome, emphasizing DNA methylation patterns and chromosomal abnormalities.
