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Explores single molecule sequencing strategies, including sequencing by synthesis and real-time sequencing based on zero mode waveguides, as well as DNA translocation through nanopores.
Covers the historical development of genomics, from Sanger sequencing to high-throughput technologies and cost reductions, highlighting the impact of key players like Craig Venter.
Explores the evolution of DNA sequencing techniques, from shotgun sequencing to real-time PCR, emphasizing the importance of direct RNA sequencing and the challenges of repetitive DNA sequences.
