Lecture
Genomic Imprinting: Disorders and Mechanisms
In course
DEMO: Lorem ut mollit id
Dolor pariatur aliquip occaecat quis dolore. Consectetur pariatur ea esse aute mollit. Mollit irure cillum aliqua consequat id in nulla consequat dolor ut duis. Qui excepteur cupidatat enim velit ex irure est tempor consectetur et aliquip. Velit adipisicing esse duis ad laboris labore aute incididunt ipsum consectetur culpa mollit ad amet. Reprehenderit eu id eiusmod commodo do in deserunt.
Description
This lecture discusses the importance of DNA methylation in genomic imprinting, focusing on cases of maternal and paternal uniparental disomy of chromosome 7. It explores the clinical manifestations of Silver-Russell syndrome and Angelman syndrome, highlighting the impact of imprinted genes on growth and neurological development. The molecular mechanisms behind monoallelic expression and the role of DNA methylation in regulating gene expression are also explained.
Instructor
veniam et dolor
Ad mollit sunt cupidatat Lorem ex labore exercitation. Magna id eiusmod commodo pariatur voluptate. Dolore Lorem sunt exercitation tempor sit laboris veniam quis minim ad aliqua tempor dolore proident. Ea non enim consectetur occaecat minim labore exercitation elit commodo enim incididunt. Dolore consequat amet mollit esse enim. Minim fugiat sit fugiat sit deserunt pariatur dolore ea fugiat minim velit deserunt.
Official source
About this result
This page is automatically generated and may contain information that is not correct, complete, up-to-date, or relevant to your search query. The same applies to every other page on this website. Please make sure to verify the information with EPFL's official sources.
Related lectures (27)
Prader-Villy Syndrome: Genetic Mechanisms and Clinical Implications
Explores the genetic basis of Prader-Villy syndrome and its comparison with Angelman syndrome, emphasizing DNA methylation patterns and chromosomal abnormalities.
Neurogenetics: Building blocks of a geneMOOC: Neuroscience Reconstructed: Cell Biology
Explores 21st-century neurogenetics and the building blocks of genes, emphasizing the impact of environment and genetics on neurodevelopment.
DNA Methylation: Mechanisms and Applications
Explores DNA methylation, its impact on gene expression, genomic imprinting, and severe combined immunodeficiency.
Epigenomics: DNA Methylation and Histone ModificationsMOOC: Neuroscience Reconstructed: Cell Biology
Delves into DNA methylation, histone modifications, epigenetic dysregulation in diseases, and techniques for studying chromatin interactions.
Angelman Syndrome: Genetic Mechanisms
Explores DNA methylation analysis and gene mutations in Angelman Syndrome.