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Explores kinase inhibitors, enzyme inhibition methods, transition state analog drugs, and the significance of covalent drugs in pharmaceutical research.
Explores drug targets, particularly nuclear receptors like PPARy and pregnane X receptor, and their impact on endocrine signaling and drug pharmacokinetics.
Explores the synthesis of sphingolipids, focusing on ceramide formation, glycosylation, and sphingomyelin conversion, as well as the biosynthesis of complex glycosphingolipids.
Explores the spontaneous emergence of self-replicating molecules containing nucleobases and amino acids, focusing on dynamic combinatorial chemistry and potential applications in inhibiting bacterial growth.