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Fluorescence lifetime imaging microscopy (FLIM) is an imaging modality often used to monitor biochemical properties of a cell or a tissue. In addition to conventional fluorescence microscopy features, such as selective labeling and non-invasiveness, FLIM e ...
In this article, the impact of the combination of the column-level gain and the correlated multiple sampling (CMS) on the noise of CMOS image sensor (CIS) readout chains is first analyzed. The theory is then validated experimentally with CIS readout chains ...
The different receptors in human skin show not only diversity in the stimuli to which they respond, but also variable sensitivity and directionality. This is often determined by their location or morphology, and can play an important role in filtering or a ...
A light microscope comprises a light source (10) for illuminating a specimen (35), a sensor array (60) comprised of photon-counting detector elements (61, 62) for measuring detection light (15) coming from the specimen (35), and a control device (70) for c ...
The present invention relates to a multispectral image sensor having a pixel array for detecting images with light components in different wavelength ranges, comprising a plurality of imaging layers each embedded in a semiconductor substrate, wherein in ea ...
A burst image sensor named Hanabi, meaning fireworks in Japanese, includes a branching CCD and multiple CMOS readout circuits. The sensor is backside-illuminated with a light/charge guide pipe to minimize the temporal resolution by suppressing the horizont ...
Rapid advances in image sensor technology have generated a mismatch between the small size of image sensor pixels and the achievable filter spectral resolution. This mismatch has prevented the realization of chip-based image sensors with simultaneously hig ...
Oxygenation is an important marker in many clinical settings, e.g. diagnosing ischaemic brain injuries in preterm infants or determining treatment effectiveness in cancer patients. Despite significant efforts to determine the oxygenation state of the human ...
The technological and experimental progress in electrochemical imaging of biological specimens is discussed with a view on potential applications for skin cancer diagnostics, reproductive medicine and microbial testing. The electrochemical analysis of sing ...
An implantable local temperature monitoring system for a laboratory mouse is presented. Magnetic coupling is used to remotely power the passive implant. The temperatures of two local points are monitored by thermistors. A low-power readout circuit is imple ...
