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A bioactive injectable bulking material; a potential therapeutic approach for stress urinary incontinence

Related publications (36)

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Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents

Johan Auwerx, Maria del Carmen Sandi Perez, Patrick Aebischer, Laurent Mouchiroud, Pénélope Andreux, Dongryeol Ryu, Evan Graehl Williams, Elena Katsyuba, Norman Lionel Moullan, Pooja Jha, Damien Sébastien Huzard, Giuseppe Lo Sasso

The biological effects of urolithins remain poorly characterized, despite wide-spread human exposure via the dietary consumption of their metabolic precursors, the ellagitannins, which are found in the pomegranate fruit, as well as in nuts and berries. We ...

Nature Publishing Group2016

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The development of thin-film dielectric elastomer strain sensors for the characterization of smooth muscle cell (SMC) contraction is presented here. Smooth muscle disorders are an integral part of diseases such as asthma and emphysema. Analytical tools ena ...

Spie-Int Soc Optical Engineering2015

Muscle force control of musculoskeletal humanoid systems has been studied for years in the motor control, biomechanics and robotics disciplines. However, the study of "load-distributed" muscle control has seldomly been contemplated. In this paper, we consi ...

Elsevier Science Bv2015

Mechanical Characterization and Shape Optimization of Fascicle-Like 3D Skeletal Muscle Tissues Contracted with Electrical and Optical Stimuli

Mahmut Selman Sakar

In this study, we present a quantitative approach to construct effective 3D muscle tissues through shape optimization and load impedance matching with electrical and optical stimulation. We have constructed long, thin, fascicle-like skeletal muscle tissue ...

2014

Background: Hypospadias and urethral strictures are conditions requiring additional tissue for reconstruction. Due to a limited source of tissue, autologous skin and oral mucosa are frequently used. However, long-term follow-up studies demonstrated signifi ...

Mary Ann Liebert, Inc2014

In this Master thesis we aim at studying some physiological and computational aspects of the excitation-contraction mechanisms in the heart muscle. This phenomenon exhibits many complexities at different spatio-temporal scales. The relevance and applicabil ...

2013

Optogenetic control of live skeletal muscles: Non-invasive, wireless, and precise activation of muscle tissues

Mahmut Selman Sakar

Optogenetics is an emerging new technology for controlling live cell function with light. Skeletal muscles are genetically coded to express light-sensitive proteins so that the cell's behavior may be altered by illuminating a targeted portion of the cell. ...

IEEE2013

Triclosan (TCS), a high volume chemical widely used in consumer products, is a known aquatic contaminant found in fish inhabiting polluted watersheds. Mammalian studies have recently demonstrated that TCS disrupts signaling between the ryanodine receptor ( ...

American Chemical Society2013

Densely arrayed skeletal myotubes are activated individually and as a group using precise optical stimulation with high spatiotemporal resolution. Skeletal muscle myoblasts are genetically encoded to express a light-activated cation channel, Channelrhodops ...

Royal Society of Chemistry2012

Triplet imaging of oxygen consumption during the contraction of a single smooth muscle cell (A7r5)

Dimitri Nestor Alice Van De Ville, Theo Lasser, Kai Johnsson, Marcel Leutenegger, Boris Hinz, Iwan Märki, Thiemo Spielmann, Aurélie Formey de Saint Louvent, Matthias Geissbühler

Triplet imaging is a novel optical technique that allows investigating oxy- gen metabolism at the single cell and the sub-cellular level. The method combines high temporal and spatial resolution, which are required for the monitoring of fast kinetics of ox ...

Springer Science+Business Media2012