Gas-phase ion chemistry

Gas phase ion chemistry is a field of science encompassed within both chemistry and physics. It is the science that studies ions and molecules in the gas phase, most often enabled by some form of mass spectrometry. By far the most important applications for this science is in studying the thermodynamics and kinetics of reactions. For example, one application is in studying the thermodynamics of the solvation of ions. Ions with small solvation spheres of 1, 2, 3... solvent molecules can be studied in the gas phase and then extrapolated to bulk solution. Transition state theory Transition state theory is the theory of the rates of elementary reactions which assumes a special type of chemical equilibrium (quasi-equilibrium) between reactants and activated complexes. RRKM theory RRKM theory is used to compute simple estimates of the unimolecular ion decomposition reaction rates from a few characteristics of the potential energy surface. The process of converting an atom or molecule into an ion by adding or removing charged particles such as electrons or other ions can occur in the gas phase. These processes are an important component of gas phase ion chemistry. Associative ionization Associative ionization is a gas phase reaction in which two atoms or molecules interact to form a single product ion. where species A with excess internal energy (indicated by the asterisk) interacts with B to form the ion AB+. One or both of the interacting species may have excess internal energy. Charge-exchange ionization Charge-exchange ionization (also called charge-transfer ionization) is a gas phase reaction between an ion and a neutral species in which the charge of the ion is transferred to the neutral. chemical ionization In chemical ionization, ions are produced through the reaction of ions of a reagent gas with other species. Some common reagent gases include: methane, ammonia, and isobutane. Chemi-ionization Chemi-ionization can be represented by where G is the excited state species (indicated by the superscripted asterisk), and M is the species that is ionized by the loss of an electron to form the radical cation (indicated by the superscripted "plus-dot").