Concept
Blood glucose monitoring
Publications associées (235)
Augmented mitochondrial energy metabolism is an early response to chronic glucose stress in human pancreatic beta cells
Loïc Dayon, Andreas Wiederkehr, Sofia Moco, Isabelle Chareyron
Aims/hypothesis In islets from individuals with type 2 diabetes and in islets exposed to chronic elevated glucose, mitochondrial energy metabolism is impaired. Here, we studied early metabolic changes and mitochondrial adaptations in human beta cells durin ...
2020Pencil Graphite Needle-Shaped Biosensor for Anaesthetic Monitoring in Human Serum
Sandro Carrara, Danilo Demarchi, Simone Aiassa
Direct and online continuous monitoring of anaesthetic intake by the patient's blood stream improves practices in the critical procedure of anaesthesia. Several systems have been proposed to address this challenge. Electrochemical techniques are highly app ...
IEEE2020Biogeography and biochemistry of bile acid 7-dehydroxylation in the mammalian gut
Bile acids (BAs) are small molecules synthesized by the host and chemically modified by the microorganisms inhabiting the intestinal tract. The microbial transformation of BAs in the gut is critical to BA-mediated signaling as it modifies their amount and ...
EPFL2020Optical microsystems for genetically engineered biosensors. Case study: Glucose monitoring
Diabetes is a global epidemic with millions of people dying from it every year. Progress in
microelectronics and machine learning has led to a huge number of FDA approvals of devices
for continuous monitoring and treatment of diabetes with one product usin ...
EPFL2019Glucose transporter 2 mediates the hypoglycemia-induced increase in cerebral blood flow
Glucose transporter 2 (Glut2)-positive cells are sparsely distributed in brain and play an important role in the stimulation of glucagon secretion in response to hypoglycemia. We aimed to determine if Glut2-positive cells can influence another response to ...
2019Pancreatic beta cell based optical biosensor and system for continuous glucose monitoring
Catherine Dehollain, Umberto De Marchi, Bakul Jitendra Vinchhi, Nicolas Bouche, Christophe Boss, Ninad Dilip Agashe
A bio-electronics system that measures cytosolic [Ca2+] in vitro in the INS-1E pancreatic beta-cells using a 430 nm excitation light with the excitation wavelength of the probe being at 435 nm was successfully implemented and tested. We transfected the INS ...
IEEE20193D-Integration Of Printed Electrochemical Sensors In Pet Microfluidics For Biochemical Sensing
Danick Briand, Peter Van der Wal, Silvia Demuru, Angélique Martine Bionaz, Marc Olivier Joho
This paper presents a novel process for screen printed electrode fabrication, functionalization and integration in a polyethylene terephthalate (PET) fluidics system for electrochemical analysis. The innovative components utilized are: 1. 3D Through-Foil V ...
IEEE2019Optical pancreatic beta cell based biosensor, applications and glucose monitoring
Catherine Dehollain, Umberto De Marchi, Bakul Jitendra Vinchhi, Nicolas Bouche, Christophe Boss
An optical pancreatic beta-cell based biosensor for measuring cytosolic [Ca2+] is presented in this work. An in vitro bio-electronic system is built for testing various applications and characterizing features of the biosensor. A panoply of applications su ...
IEEE2019Bioluminescent-based imaging and quantification of glucose uptake in vivo
Riccardo Sinisi, Elena Goun, Pavlo Khodakivskyi, Arkadiy Bazhin, Aleksey Yevtodiyenko, Tamara Maric, Georgy Mikhaylov
Glucose is a major source of energy for most living organisms, and its aberrant uptake is linked to many pathological conditions. However, our understanding of disease-associated glucose flux is limited owing to the lack of robust tools. To date, positron- ...
NATURE PUBLISHING GROUP2019Protein Bioconjugation to Carbon Nanotubes for Near-Infrared Sensing
Single-walled carbon nanotubes (SWCNTs) are a promising material for electrochemical and optical biosensing applications. Their small dimensions, large surface area, indefinite photostability, and remarkable electronic properties make SWCNTs an ideal trans ...
EPFL2019