Sarah Catherine Sonnay

Cette personne n’est plus à l’EPFL

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Publications associées (19)

Alterations of brain energy metabolism in insulin-resistant Goto-Kakizaki rats measured in vivo by C-13 magnetic resonance spectroscopy

João Miguel das Neves Duarte, Sarah Catherine Sonnay, Freya-Merret Girault

Springer2017

Rates oxidative metabolism in astrocytes and neurons are coupled to the glutamate-glutamine cycle in the tree shrew visual cortex

Rolf Gruetter, Nathalie Just, João Miguel das Neves Duarte, Sarah Catherine Sonnay, Anne Catherine Clerc

Wiley2017

Compartmentalised energy metabolism supporting glutamatergic neurotransmission in response to increased activity in the rat cerebral cortex: A 13C MRS study in vivo at 14.1 T

Rolf Gruetter, Nathalie Just, João Miguel das Neves Duarte, Sarah Catherine Sonnay

Many tissues exhibit metabolic compartmentation. In the brain, while there is no doubt on the importance of functional compartmentation between neurons and glial cells, there is still debate on the specific regulation of pathways of energy metabolism at di ...

Nature Publishing Group2016

Assessment of brain metabolite correlates of AAV-mediated overexpression of human alpha-synuclein in cortical neurons by in vivo(1) H-MR spectroscopy at 9.4 T

Sarah Catherine Sonnay

In this study, we used proton-localized spectroscopy ((1) H-MRS) for the acquisition of the neurochemical profile longitudinally in a novel rat model of human wild type alpha-synuclein (a-syn) overexpression. Our goal was to find out if the increased a-syn ...

Wiley-Blackwell2016

Imaging of prolonged BOLD response in the somatosensory cortex of the rat

Rolf Gruetter, Nathalie Just, João Miguel das Neves Duarte, Sarah Catherine Sonnay

Blood oxygenation level-dependent (BOLD) functional MRI is a widely employed methodology in experimental and clinical neuroscience, although its nature is not fully understood. To gain insights into BOLD mechanisms and take advantage of the new functional ...

Wiley-Blackwell2015

Energy metabolism in the rat cortex under deep thiopental anesthesia measured in vivo by 13C MRS at 14.1 T

Rolf Gruetter, Nathalie Just, João Miguel das Neves Duarte, Sarah Catherine Sonnay

Wiley-Blackwell2015

PARK9-associated ATP13A2 localizes to intracellular acidic vesicles and regulates cation homeostasis and neuronal integrity

Liliane Glauser, Elpida Tsika, Klodjan Stafa, Darren Moore, Alzbeta Trancikova, Sarah Catherine Sonnay, Agata Podhajska, David Ramonet Jimenez

Mutations in the ATP13A2 gene (PARK9, OMIM 610513) cause autosomal recessive, juvenile-onset Kufor-Rakeb syndrome and early-onset parkinsonism. ATP13A2 is an uncharacterized protein belonging to the P-5-type ATPase subfamily that is predicted to regulate t ...

Oxford University Press2012

Common Pathogenic Effects of Missense Mutations in the P-Type ATPase ATP13A2 (PARK9) Associated with Early-Onset Parkinsonism

Liliane Glauser, Alessandra Musso, Darren Moore, Sarah Catherine Sonnay, Klodjan Stafa, Alzbeta Trancikova, Agata Podhajska

Mutations in the ATP13A2 gene (PARK9) cause autosomal recessive, juvenile-onset Kufor-Rakeb syndrome (KRS), a neurodegenerative disease characterized by parkinsonism. KRS mutations produce truncated forms of ATP13A2 with impaired protein stability resultin ...

Public Library of Science2012

Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1

Liliane Glauser, Darren Moore, Sarah Catherine Sonnay, Klodjan Stafa

Mutations in the parkin gene cause early-onset, autosomal recessive Parkinson's disease. Parkin functions as an E3 ubiquitin ligase to mediate the covalent attachment of ubiquitin monomers or linked chains to protein substrates. Substrate ubiquitination ca ...

2011

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