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The design, fabrication and characterization of CMOS-compatible optoelectronic devices is discussed. All devices are fabricated on silicon on insulator (SOI) substrates which makes them suitable for three-dimensional (3-D) telecommunication photonic integr ...
A major challenge to understanding behavior is how the nervous system allows the learning of behavioral sequences that can occur over arbitrary timescales, ranging from milliseconds up to seconds, using a fixed millisecond learning rule. This article descr ...
Growing neurites are guided through their environment during development and regeneration via different cellular and extracellular matrix (ECM) molecular cues. To mimic cell-matrix interactions, a three-dimensional (3D) hydrogel-based ECM equivalent contai ...
A three-dimensional generalization of a Potts pseudo-atomic model based on a stochastic process has been implemented on a CRAY-2 computer to study large networks during long simulations. The three-dimensional network was then sampled with two-dimensional c ...
Three principles of optimal energy expenditure are used to derive the most important structural characteristics observed in drainage networks: (1) the principle of minimum energy expenditure in any link of the network, (2) the principle of equal energy exp ...
The phenotypic expression of various neural cells is influenced by extracellular matrix (ECM) molecules. This study aims to develop a three-dimensional gel tailored to support neurite extension from neural cells. Laminin-derived (LN) oligopeptides CDP-GYIG ...
BACKGROUND: Notch signaling regulates multiple differentiation processes and cell fate decisions during both invertebrate and vertebrate development. Numb encodes an intracellular protein that was shown in Drosophila to antagonize Notch signaling at binary ...
Brain-derived neurotrophic factor (BDNF) is a 27-kDa basic protein of noncovalently linked 13.5-kD subunits related to nerve growth factor and is produced by the central nervous system (CNS). BDNF has been shown to promote the survival of neurons located i ...