Single-photon avalanche diode imagers in biophotonics: review and outlook
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New advances in the field of image sensors (especially in CMOS technology) tend to question the conventional methods used to acquire the image. Compressive Sensing (CS) plays a major role in this, especially to unclog the Analog to Digital Converters which ...
Imaging techniques based on time-correlated single photon counting (TCSPC), such as fluorescence lifetime imaging microscopy (FLIM), rely on fast single-photon detectors as well as timing electronics in the form of time-to-digital or time-to-analog convert ...
Spie-Int Soc Optical Engineering, Po Box 10, Bellingham, Wa 98227-0010 Usa2010
In the past decades different methods based on magnetic resonance imaging (MRI) and positron emission tomography (PET) have been developed to image a variety of hemodynamic parameters in tissue. However, simultaneous high resolution imaging of oxy- and deo ...
In recent years, modern imaging sensors and systems have become increasingly complex following the growing demand for high-quality and high-resolution imaging. Commercially available sensors having 30-40 mega-pixel resolutions are common nowadays, while pr ...
LinoSPAD is a reconfigurable camera sensor with a 256x 1 CMOS SPAD (single-photon avalanche diode) pixel array connected to a low cost Xilinx Spartan 6 FPGA. The LinoSPAD sensor's line of pixels has a pitch of 24 pm and 40% fill factor. The FPGA implements ...
We propose a technique to localize computation in Instruction Set Extensions (ISEs) that are clocked at very high speed with respect to the processor. In order to save power, data to and from Custom Instruction Units (CIUs) is synchronized via an optical s ...
Since the first introduction of digital cameras, the camera market has been taking tremendous interest from many fields. This trend has even accelerated when the cost, size, and power consumption of such devices were reduced with the introduction of camera ...
The advent of single-photon detectors known as Single-Photon Avalanche Diodes in standard CMOS technology opened the way to new perspectives in integrating these ultra sensitive light sensors with digital logic. Light has some interesting properties that a ...
We incorporate newly developed solid-state detector technology into time-resolved laser Raman spectroscopy, demonstrating the ability to distinguish spectra from Raman and fluorescence processes. As a proof of concept, we show fluorescence rejection on hig ...
This paper presents an on-chip, filter-less fluorescence detector using an all-digital, time-resolved imager based on a CMOS single-photon detector array with limited in situ processing. The device comprises an array of pixels capable of detecting single p ...