Separation of overlapping multiplets in a two-dimensional NMR spectrum by injection of magnetization

A SPLIT-COSY (SPLIT = sepn. of patterns by lifting of the imbroglio of transfer) technique is proposed for the sepn. of overlapping multiplets in the signal-rich region of a COSY spectra. This technique is particularly suitable for isomeric mixts. Results are reported for cyclo(L-pro1-L-pro2-D-pro3). [on SciFinder (R)]