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This lecture covers the concept of liquid-liquid partitioning, focusing on the partitioning of compounds between different phases. It discusses the thermodynamics and general theory behind partitioning, including liquid-liquid, air-liquid, and liquid-solid partitioning. Special cases like aqueous solubility and octanol-water partitioning are also explored, along with the influence of temperature and salinity on partition constants. The lecture delves into the mechanisms of solubility and the factors affecting solubility, such as chain length, size, and halogenation. Various exercises are presented to apply the theoretical concepts to practical scenarios.
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