Concept
Human evolution
Related publications (85)
Les fumées des trains à vapeur, un débordement industriel et professionnel (France, Grande-Bretagne, années 1860-1930)
Objet d’une héroïsation précoce et durable, notamment à travers la littérature, le travail des mécaniciens et chauffeurs de locomotives à vapeur reste mal connu du point de vue de ses effets sur l’environnement et sur la santé des travailleurs eux-mêmes. ...
2024SORI: A softness-rendering interface to unravel the nature of softness perception
Jamie Paik, Mustafa Mete, Hwayeong Jeong
Tactile perception of softness serves a critical role in the survival, well-being, and social interaction among various species, including humans. This perception informs activities from food selection in animals to medical palpation for disease detection ...
Natl Acad Sciences2024Bacterial diversity dominates variable macrophage responses of tuberculosis patients in Tanzania
The Mycobacterium tuberculosis complex (MTBC) comprises nine human-adapted lineages that differ in their geographical distribution. Local adaptation of specific MTBC genotypes to the respective human host population has been invoked in this context. We aim ...
Nature Portfolio2024Secondary structure of the human mitochondrial genome affects formation of deletions
Jacques Fellay, Konstantin Popadin
BackgroundAging in postmitotic tissues is associated with clonal expansion of somatic mitochondrial deletions, the origin of which is not well understood. Such deletions are often flanked by direct nucleotide repeats, but this alone does not fully explain ...
BMC2023Higher-order organization of multivariate time series
Time series analysis has proven to be a powerful method to characterize several phenomena in biology, neuroscience and economics, and to understand some of their underlying dynamical features. Several methods have been proposed for the analysis of multivar ...
NATURE PORTFOLIO2023Development and validation of an expanded antibody toolset that captures alpha-synuclein pathological diversity in Lewy body diseases
Hilal Lashuel, Johannes Burtscher, Melek Firat Altay, Somanath Jagannath
The abnormal aggregation and accumulation of alpha-synuclein (aSyn) in the brain is a defining hallmark of synucleinopathies. Various aSyn conformations and post-translationally modified forms accumulate in pathological inclusions and vary in abundance amo ...
Berlin2023Mitochondrial Pseudogenes Suggest Repeated Inter-Species Hybridization among Direct Human Ancestors
The hypothesis that the evolution of humans involves hybridization between diverged species has been actively debated in recent years. We present the following novel evidence in support of this hypothesis: the analysis of nuclear pseudogenes of mtDNA ("NUM ...
MDPI2022