Somatic evolution in cancer

Natural sciences
Biology
Genetics
Molecular genetics

Natural sciences
Biology
Cell biology
Cancer

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Related lectures (16)

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Immune Selection and Cancer Evolution

Delves into immune selection, cancer evolution, neoantigen quality, fitness cost, tumor heterogeneity, and evolutionary predictions.

Cancer Genomics: Comprehensive Molecular Characterization and Evolution

Explores comprehensive genomic characterization, mutual exclusivity, and cancer evolution.

Genetic Instability: De Palma

Explores genetic instability in cancer, multi-step progression, repair mechanisms, and cancer stem cells.

Evading Growth Suppression: TGFB Signaling

Explores how cells evade growth suppression, focusing on TGFB signaling and the role of tumor suppressors like PTEN and p53.

Hallmarks of Cancer: Complexity and Capabilities

Explores the complexity and fundamental capabilities of cancer, focusing on hallmarks like sustained proliferative signaling and evading growth suppressors.

Understanding Cancer Genetics

Explores genetic and epigenetic changes in cancer cells and the impact of carcinogens.

DNA Damage Response and Tumor Suppressor Genes

Delves into DNA damage response, tumor suppressor genes, and mutant P53 in cancer.

Chemical Biology Fundamentals: Covalent Drug Efficacy

Delves into the efficacy of covalent drugs in chemical biology, exploring reversible vs. irreversible binders and mechanism-based inactivators.

Mechanobiology of Cancer

Delves into how mechanical forces impact cancer progression through nuclear size control, matrix stiffness, and metastasis.

Cancer Biology: Hallmarks and Mechanisms

Covers the hallmarks of cancer, oncogenes, tumor suppressor genes, metastasis, and genetic alterations driving tumorigenesis.