P200

In neuroscience, the visual P200 or P2 is a waveform component or feature of the event-related potential (ERP) measured at the human scalp. Like other potential changes measurable from the scalp, this effect is believed to reflect the post-synaptic activity of a specific neural process. The P2 component, also known as the P200, is so named because it is a positive going electrical potential that peaks at about 200 milliseconds (varying between about 150 and 275 ms) after the onset of some external stimulus. This component is often distributed around the centro-frontal and the parieto-occipital areas of the scalp. It is generally found to be maximal around the vertex (frontal region) of the scalp, however there have been some topographical differences noted in ERP studies of the P2 in different experimental conditions. Research on the visual P2 is at an early stage compared to other more established ERP components and there is much that we still do not know about it. Part of the difficulty of clearly characterizing this component is that it appears to be modulated by a large and diverse number of cognitive tasks. Functionally, there seems to be partial agreement amongst researchers in the field of cognitive neuroscience that the P2 represents some aspect of higher-order perceptual processing, modulated by attention. It is known that the P2 is typically elicited as part of the normal response to visual stimuli and has been studied in relation to visual search and attention, language context information, and memory and repetition effects. The amplitude of the peak of the waveform may be modulated by many different aspects of visual stimuli, which allow it to be used for studies of visual cognition and disease. In general, the P2 may be a part of cognitive matching system that compares sensory inputs with stored memory. The first mentions of an ERP component similar to that of the modern P2 were characterized in studies of basic visual and auditory evoked potentials. One of the first of such studies involved the presentation of flashing lights.

20-years work investigating the shine-through paradigm in the schizophrenia spectrum: what is next?

High levels of childhood trauma associated with changes in hippocampal functional activity and connectivity in young adults during novelty salience

Comparison of Responses to DCN vs. VCN Stimulation in a Mouse Model of the Auditory Brainstem Implant (ABI)

High levels of childhood trauma associated with changes in hippocampal functional activity and connectivity in young adults during novelty salience

Comparison of Responses to DCN vs. VCN Stimulation in a Mouse Model of the Auditory Brainstem Implant (ABI)

20-years work investigating the shine-through paradigm in the schizophrenia spectrum: what is next?