Concept

Vascular surgery

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Compliant vascular grafts and methods of use

Nikolaos Stergiopoulos, Georgios Rovas

Compliant vascular grafts for implantation in the vasculature are provided. The compliant vascular grafts are designed to expand longitudinally and radially within a blood vessel, such as an artery, and is expected to be particularly well suited for treati ...

2024

Fast-Response Variable-Stiffness Magnetic Catheters for Minimally Invasive Surgery

Dario Floreano, Yegor Piskarev, Jun Shintake, Yi Sun, Matteo Righi

In minimally invasive surgery, such as cardiac ablation, magnetically steered catheters made of variable-stiffness materials can enable higher dexterity and higher force application to human tissue. However, the long transition time between soft and rigid ...

2024

Modified pressure-cooker technique (PCT) using extra-soft Kaneka coils improves embolization of high-grade cerebral arteriovenous malformations: a technical note

Mahmut Yüksel

Endovascular embolization techniques are showing an extraordinary potential to treat patients suffering from complex neurovascular malformations. The embolization with liquid embolic agents via Onyx is a prominent approach to treat arteriovenous malformati ...

SPRINGERNATURE2023

Microvascular stalling, the process occurring when a capillary temporarily loses perfusion, has gained increasing interest in recent years through its demonstrated presence in various neuropathologies. Studying the impact of such stalls on the surrounding ...

2023

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A hollow variable stiffness thread including a flexible inner tube, a conductive shape memory polymer (CSMP) layer arranged around the inner tube forming a variable stiffness zone, a flexible encapsulation layer arranged around the CSMP layer, and a first ...

2023

Use of autologous cells isolated from elderly patients with multiple comorbidities may account for the modest efficacy of cell therapy in patients with chronic limb threatening ischemia (CLTI). We aimed to determine whether proarteriogenic monocyte/macroph ...

Ann Arbor2023

Arterial pulse waves (PWs) such as blood pressure and photoplethysmogram (PPG) signals contain a wealth of information on the cardiovascular (CV) system that can be exploited to assess vascular age and identify individuals at elevated CV risk. We review th ...

AMER PHYSIOLOGICAL SOC2023

Design and computational optimization of compliance-matching aortic grafts

Nikolaos Stergiopoulos, Georgios Rovas, Vasiliki Bikia

Introduction: Synthetic vascular grafts have been widely used in clinical practice for aortic replacement surgery. Despite their high rates of surgical success, they remain significantly less compliant than the native aorta, resulting in a phenomenon calle ...

FRONTIERS MEDIA SA2023

Comparing end-tidal CO2, respiration volume per time (RVT), and average gray matter signal for mapping cerebrovascular reactivity amplitude and delay with breath-hold task BOLD fMRI

Stefano Moia

Cerebrovascular reactivity (CVR), defined as the cerebral blood flow response to a vasoactive stimulus, is an imaging biomarker with demonstrated utility in a range of diseases and in typical development and aging processes. A robust and widely implemented ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2023

On the similarity between aortic and carotid pressure diastolic decay: a mathematical modelling study

Nikolaos Stergiopoulos, Georgios Rovas, Sokratis Anagnostopoulos, Vasiliki Bikia

Aortic diastolic pressure decay (DPD) has been shown to have considerable pathophysiological relevance in the assessment of vascular health, as it is significantly affected by arterial stiffening. Nonetheless, the aortic pressure waveform is rarely availab ...

NATURE PORTFOLIO2023