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Lecture
Biomolecular Condensation: Hsf1 in Stress Response
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Early Events in the Heat Shock Response: Action in the Nucleus
Explores early events in the Heat Shock Response, focusing on Hsf1 regulation, Hsp70 dynamics, and the role of Sis1.
Heat Shock Transcription Factors: Regulation and Targets
Explores Heat Shock Transcription Factors' regulation and targets in response to stress, including HSF2's dynamic expression and impact on cell adhesion.
Prokaryotic Transcription: Operons and Sigma Factors
Explores prokaryotic transcription, operons, sigma factors, gene regulation, and DNA loops in bacteria.
Protein Disaggregation by Hsp70 Chaperone System
Explores protein disaggregation by the Hsp70 chaperone system and the significance of aggregate modification for protein refolding.
DNA Structure and Gene Expression
Explores DNA structure, gene expression, RNA transcription, and protein manufacturing in cells, including the crucial role of RNA polymerase.
DNA Structure and Transcription
Explores DNA structure, replication, transcription, mRNA translation, and gene expression regulation.
Hsp70 Interaction with Measles Virus Nucleoprotein
Explores the interaction between hsp70 and the intrinsically disordered Ntail domain of the measles virus nucleoprotein.
Molecular Mechanism of Hsp70 Chaperones: Interactions with Cochaperones and Substrates
Explores the molecular mechanism of Hsp70 chaperones, focusing on interactions with cochaperones and substrates.
RNA Functions: Transcription and Translation
Explores RNA functions in transcription, translation, and gene regulation, including defense mechanisms and viral infections.
Cellular Heat Shock Response: Rethinking the Significance
Delves into the cellular heat shock response, emphasizing the absence of a sensor mechanism and the restoration of misfolded protein aggregates.