Evading Growth Suppression: TGFB Signaling

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Explores altered cancer metabolism, MYC regulation, Rb and p53 pathways, AKT re-activation, and protein-protein interactions.

Explores the tumor microenvironment, stromal components, cell interactions, and the impact of inflammation on cancer promotion.

Explores the multi-step progression of tumors, from cancer incidence rates to tumor initiators and promoters.

Explores the RTK/PI3K/mTOR pathway in cancer, inhibitors, completed trials, and effects of Akt/PKB on survival and proliferation.

Covers cancer biology topics on base excision repair, cellular responses to DNA damage, p53 regulation, and apoptosis mechanisms.

Explores the mechanisms of cancer invasion and metastasis, emphasizing the critical role of cell adhesion, signaling rewiring, and organotropism.

Explores DNA repair mechanisms, DNA damage response, and synthetic lethality in cancer.

Explores the basics of radiotherapy, including biological principles, types, techniques, and classical methods used in fighting cancer.

Explores human tumor suppressor genes and genetic predisposition to cancer, using retinoblastoma as a model for tumor formation.

Explores metabolic signaling, the Warburg effect, and pathway rewiring in proliferating cells.