Replicative Immortality

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Related lectures (31)

Page 1 of 4

Explores telomeres' role in cancer biology, covering telomerase, replication problems, ALT pathway, and Nobel Prize-winning discoveries.

Cellular Senescence and Tumor Progression

Explores cellular senescence, oncogene activation, DNA damage response, and telomere dysfunction in cancer suppression pathways.

Cellular Senescence: Mechanisms and Implications

Explores cellular senescence mechanisms induced by mitogenic signals, DNA damage, and oncogenes, emphasizing the role of key regulatory proteins and the impact on cell division.

Cancer Biology: Hallmarks and Mechanisms

Covers the hallmarks of cancer, oncogenes, DNA repair, telomeres, viruses, cell cycle, stem cells, metastasis, and genetic instability.

Cancer Biology: Base Excision Repair

Covers cancer biology topics on base excision repair, cellular responses to DNA damage, p53 regulation, and apoptosis mechanisms.

DNA Structure and Function

Explores DNA structure, histone interactions, polymerase function, nucleosome organization, chromatin compaction, cell cycle phases, FISH analysis, and telomere structure.

Evading Growth Suppression: TGFB Signaling

Explores how cells evade growth suppression, focusing on TGFB signaling and the role of tumor suppressors like PTEN and p53.

Tumor Suppressor p53

Explores the tumor suppressor gene p53, its functions, regulation, and implications for cancer.

Telomeres and Cancer

Explores telomeres' crucial role in cancer biology, covering telomerase, replication problems, ALT pathway, and TERRA functions.

Telomere damage response

Discusses the telomere damage response and the interplay between ATM and ATR kinases.