by Prof. Lutolf

Laboratory

Summary

The Laboratory by Prof. Lutolf focuses on understanding how cells interact to build tissues and organs using organoids. They employ cutting-edge bioengineering strategies to guide stem-cell-based development for next-generation organoids with improved reproducibility and physiological relevance. Their research contributes to a better understanding of multicellular self-organization principles, with implications for drug discovery and regenerative medicine.

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Related people (88)

Related research domains (16)

Related publications (38)

In vitro endoderm emergence and self-organisation in the absence of extraembryonic tissues and embryonic architecture

Stefano Davide Vianello

In humans, mice, and other mammals key internal organs such as the gut, the lungs, the pancreas, and the liver all derive from the same embryonic tissue: the endoderm. The development of all of these

EPFL2022

Engineering next generation organoids through guided stem cell self-organisation

Mikhail Nikolaev

One of the long-standing goals in the field of tissue engineering is the fabrication of de novo tissues or even organs to provide better tissue models for basic research and drug discovery, and to al

EPFL2021

Engineering Dynamic Hydrogels For In Vitro Organoid Culture

Delphine Lorraine Perle Blondel

Over the past decade, methods to culture stem cells in three dimensions have opened up a plethora of new opportunities for basic and translational research in the life sciences. In particular, the use

EPFL2019