Concept
Protein kinase
Related lectures (46)
Protein Phosphorylation: Mechanisms and Regulation
Explores protein phosphorylation, its structural effects, kinase activity, and its role in signaling and disease.
Protein Phosphorylation: Mechanisms & Regulation
Explores protein phosphorylation, detailing common modifications like acetylation and ubiquitination, kinase specificity, and activation mechanisms.
Post-translational Modifications of Proteins
Provides an overview of protein post-translational modifications, including phosphorylation, ubiquitination, and acylation.
Posttranslational Modifications: Phosphorylation and Protein Phosphatases
Covers posttranslational modifications, focusing on phosphorylation and protein phosphatases, and explains kinase specificity assays and the optimal phosphorylation consensus.
Cell Signalling: Receptors and Pathways
Explores cell signalling mechanisms, including receptors, pathways, and signal transduction for gene regulation and cellular responses.
Tyrosine Kinases & Ras Signaling
Explores tyrosine kinases, Ras activation, lipid signaling, cancer implications, and signal transduction in cells.
Receptor Tyrosine Kinases: Signalling and Regulation
Explores the activation, signalling cascades, and regulatory mechanisms of receptor tyrosine kinases, with a focus on disease implications and therapeutic strategies.
SEGREGATION of KINETIC REACTIVITY & BINDING AFFINITY
The paper focuses on the importance of reversible interactions to potency and mechanisms of drug resistance.
Proteomics Profiling Methods
Explores proteomics profiling methods, including ABPP, MS approaches, and quantitative target identification using SILAC and TMT labeling.
Receptors and Targeting
Explores receptors, ligands, and their role in signal transduction, including the activation of the immune system and the significance of multivalency in receptor-ligand interactions.