Lecture
Tyrosine Kinases & Ras Signaling
Related lectures (36)
Protein Phosphorylation: Mechanisms and Regulation
Explores protein phosphorylation, its structural effects, kinase activity, and its role in signaling and disease.
Receptor Tyrosine Kinases: Signalling and Regulation
Explores the activation, signalling cascades, and regulatory mechanisms of receptor tyrosine kinases, with a focus on disease implications and therapeutic strategies.
Cell Signalling: Receptors and Pathways
Explores cell signalling mechanisms, including receptors, pathways, and signal transduction for gene regulation and cellular responses.
Protein Phosphorylation: Mechanisms & Regulation
Explores protein phosphorylation, detailing common modifications like acetylation and ubiquitination, kinase specificity, and activation mechanisms.
Membrane Binding Domains: PIP Signaling Pathway
Explores the role of membrane binding domains in the PIP signaling pathway and the recognition of PIPx species by specific domains.
Post-translational Modifications of Proteins
Provides an overview of protein post-translational modifications, including phosphorylation, ubiquitination, and acylation.
Cellular Communication: Signaling Pathways and Receptors
Delves into the importance of intercellular communication and the diverse signaling pathways involved in cellular responses.
Sustained Proliferation: RTK/PI3K/mTOR Pathway in Cancer
Explores the RTK/PI3K/mTOR pathway in cancer, inhibitors, completed trials, and effects of Akt/PKB on survival and proliferation.
Sustained Proliferation: Signaling Pathways and Cancer Genes
Covers sustaining proliferation in cancer cells, growth factors, receptor tyrosine kinases, signal transduction, viral oncogenes, and therapeutic opportunities.
Posttranslational Modifications: Phosphorylation and Protein Phosphatases
Covers posttranslational modifications, focusing on phosphorylation and protein phosphatases, and explains kinase specificity assays and the optimal phosphorylation consensus.