Explores receptors, ligands, and their role in signal transduction, including the activation of the immune system and the significance of multivalency in receptor-ligand interactions.
Covers sustaining proliferation in cancer cells, growth factors, receptor tyrosine kinases, signal transduction, viral oncogenes, and therapeutic opportunities.
Covers posttranslational modifications, focusing on phosphorylation and protein phosphatases, and explains kinase specificity assays and the optimal phosphorylation consensus.
