Explores the applications of CRISPR-Cas in genome editing, focusing on engineering bacterial genomes, curing genetic diseases, guide RNA simplicity, Cas9 specificity, DNA damage mechanisms, and base editing.
Explores the evolution and function of protein-repair machineries, emphasizing the role of ATP-fueled unfolding machines in preventing protein aggregation and promoting proper folding.
Explores the genetic mechanisms of retinoblastoma and their clinical implications, shedding light on tumor suppression, DNA repair, and genetic recombination.
Explores DNA replication mechanisms, including speed, errors, proofreading, and semiconservative nature, emphasizing the importance of maintaining DNA fidelity through mismatch repair.
