Drug Target Discovery: Thermal Shift Profiling

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Identifying Drug Targets with Thermal-Shift Profiling

Showcases correlations between different organs' thermal profiles to identify drug targets.

Quantitative Proteome Profiling: Chemical Target Identification

Explores quantitative proteome profiling for drug target identification through activity-based protein profiling and advanced mass spectrometry techniques.

Fragment-Based Drug Discovery: Concepts & Technologies

Covers the concepts and technologies of fragment-based drug discovery, hit identification methods, and its application in target-based drug discovery.

Protein Therapeutics: Blood Proteins and Enzymes

Explores blood composition, proteins, coagulation, diseases treated with enzymes, and case studies on genetic disorders.

Proteomics: Post-Translational Modifications and Interactions

Explores proteomics for post-translational modifications and protein interactions.

Proteomics Profiling Methods

Explores proteomics profiling methods, including ABPP, MS approaches, and quantitative target identification using SILAC and TMT labeling.

Fragment-Based Drug Discovery: Concepts & Technologies

Covers the concepts and technologies of fragment-based drug discovery, exploring hit identification, lead optimization, and screening methods.

Activity-based Protein Profiling: Druggable Sites Identification

Explores Activity-based Protein Profiling for druggable site identification and strategies to minimize off-target reactivity of covalent inhibitors.

Protein Mass Spectrometry and Proteomics: Techniques and Applications

Explores protein mass spectrometry techniques, including labeling methods, quantitation, and biomarker discovery.

Protein Mass Spectrometry and Proteomics

Covers protein mass spectrometry, proteomics techniques, challenges, and applications in analyzing complex protein mixtures.