Concept
Serine/threonine-specific protein kinase
Related lectures (31)
Protein Phosphorylation: Mechanisms and Regulation
Explores protein phosphorylation, its structural effects, kinase activity, and its role in signaling and disease.
Posttranslational Modifications: Phosphorylation and Protein Phosphatases
Covers posttranslational modifications, focusing on phosphorylation and protein phosphatases, and explains kinase specificity assays and the optimal phosphorylation consensus.
Protein Phosphorylation: Mechanisms & Regulation
Explores protein phosphorylation, detailing common modifications like acetylation and ubiquitination, kinase specificity, and activation mechanisms.
SEGREGATION of KINETIC REACTIVITY & BINDING AFFINITY
The paper focuses on the importance of reversible interactions to potency and mechanisms of drug resistance.
Altered Metabolism in Cancer: Warburg Effect and MYC Regulation
Explores altered cancer metabolism, MYC regulation, Rb and p53 pathways, AKT re-activation, and protein-protein interactions.
Cell Signalling: Receptors and Pathways
Explores cell signalling mechanisms, including receptors, pathways, and signal transduction for gene regulation and cellular responses.
Tyrosine Kinases & Ras Signaling
Explores tyrosine kinases, Ras activation, lipid signaling, cancer implications, and signal transduction in cells.
DNA Damage Checkpoint
Explores the DNA damage checkpoint, cell cycle regulation, repair mechanisms, and key proteins involved.
Post-translational Modifications of Proteins
Provides an overview of protein post-translational modifications, including phosphorylation, ubiquitination, and acylation.
Telomere damage response
Discusses the telomere damage response and the interplay between ATM and ATR kinases.