Covers mutations, classification, causes, and repair mechanisms of DNA, including spontaneous and induced mutations, replication errors, and DNA damage.
Explores p53's pivotal role in cellular stability, DNA repair, and tumor suppression, emphasizing TP53 mutations and DNA double-strand break repair mechanisms.
Explores DNA repair mechanisms, including BER, MMR, NER, and repair of double-strand breaks, as well as the impact of UV-induced lesions and resistance to PARP inhibitors.
Explores DNA repair mechanisms, focusing on BER and NER, cellular responses to DNA damage, and genetic disorders impacting DNA repair and cancer susceptibility.
Explores the genetic mechanisms of retinoblastoma and their clinical implications, shedding light on tumor suppression, DNA repair, and genetic recombination.