Proteomic Applications in Neuroscience: Targeting Cortical Neurons

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Protein Phosphorylation: Mechanisms & Regulation

Explores protein phosphorylation, detailing common modifications like acetylation and ubiquitination, kinase specificity, and activation mechanisms.

Proteomics: Post-Translational Modifications and Interactions

Explores proteomics for post-translational modifications and protein interactions.

Protein Phosphorylation: Mechanisms and Regulation

Explores protein phosphorylation, its structural effects, kinase activity, and its role in signaling and disease.

Posttranslational Modifications: Phosphorylation and Protein Phosphatases

Covers posttranslational modifications, focusing on phosphorylation and protein phosphatases, and explains kinase specificity assays and the optimal phosphorylation consensus.

Proteomics in Neuroscience: Techniques and Applications

Covers proteomics techniques and their applications in neuroscience, focusing on mass spectrometry and the challenges of studying proteins in cellular functions.

Nuclear Receptors: Signalling and Health Implications

Explores nuclear receptors, JAK-STAT pathway, growth factors, endocrine disruptors, and estrogen receptors.

SEGREGATION of KINETIC REACTIVITY & BINDING AFFINITY

The paper focuses on the importance of reversible interactions to potency and mechanisms of drug resistance.

Protein Function Regulation: Degradation Mechanisms

Covers the mechanisms of protein degradation, including the roles of the proteasome and autophagy in regulating protein function.

Protein Life Cycle

Covers gene expression, protein life cycle, and genetic code in neuroscience.

Tyrosine Kinases & Ras Signaling

Explores tyrosine kinases, Ras activation, lipid signaling, cancer implications, and signal transduction in cells.