Explores p53's pivotal role in cellular stability, DNA repair, and tumor suppression, emphasizing TP53 mutations and DNA double-strand break repair mechanisms.
Explores the genetic mechanisms of retinoblastoma and their clinical implications, shedding light on tumor suppression, DNA repair, and genetic recombination.
Explores the genetic basis of Prader-Villy syndrome and its comparison with Angelman syndrome, emphasizing DNA methylation patterns and chromosomal abnormalities.
Delves into the molecular basis of genetic diseases, discussing specific examples like Phenylketonuria and Haemophilia A, and the development of small molecule drugs for genetic disorders.
